diff --git a/test/link/macho/uuid/build.zig b/test/link/macho/uuid/build.zig
index 0c493ed80d..f188b1fad8 100644
--- a/test/link/macho/uuid/build.zig
+++ b/test/link/macho/uuid/build.zig
@@ -5,23 +5,45 @@ const LibExeObjectStep = std.build.LibExeObjStep;
 pub fn build(b: *Builder) void {
     const test_step = b.step("test", "Test");
     test_step.dependOn(b.getInstallStep());
-    testUuid(b, test_step, .ReleaseSafe, "46b333df88f5314686fc0cba3b939ca8");
-    testUuid(b, test_step, .ReleaseFast, "46b333df88f5314686fc0cba3b939ca8");
-    testUuid(b, test_step, .ReleaseSmall, "46b333df88f5314686fc0cba3b939ca8");
+
+    // We force cross-compilation to ensure we always pick a generic CPU with constant set of CPU features.
+    const aarch64_macos = std.zig.CrossTarget{
+        .cpu_arch = .aarch64,
+        .os_tag = .macos,
+    };
+
+    testUuid(b, test_step, .ReleaseSafe, aarch64_macos, "46b333df88f5314686fc0cba3b939ca8");
+    testUuid(b, test_step, .ReleaseFast, aarch64_macos, "46b333df88f5314686fc0cba3b939ca8");
+    testUuid(b, test_step, .ReleaseSmall, aarch64_macos, "46b333df88f5314686fc0cba3b939ca8");
+
+    const x86_64_macos = std.zig.CrossTarget{
+        .cpu_arch = .x86_64,
+        .os_tag = .macos,
+    };
+
+    testUuid(b, test_step, .ReleaseSafe, x86_64_macos, "342ac765194131e1bad5692b9e0e54a4");
+    testUuid(b, test_step, .ReleaseFast, x86_64_macos, "342ac765194131e1bad5692b9e0e54a4");
+    testUuid(b, test_step, .ReleaseSmall, x86_64_macos, "f119310e24773ecf8ec42e09d0379dad");
 }
 
-fn testUuid(b: *Builder, test_step: *std.build.Step, mode: std.builtin.Mode, comptime exp: []const u8) void {
+fn testUuid(
+    b: *Builder,
+    test_step: *std.build.Step,
+    mode: std.builtin.Mode,
+    target: std.zig.CrossTarget,
+    comptime exp: []const u8,
+) void {
     // The calculated UUID value is independent of debug info and so it should
     // stay the same across builds.
     {
-        const dylib = simpleDylib(b, mode);
+        const dylib = simpleDylib(b, mode, target);
         const check_dylib = dylib.checkObject(.macho);
         check_dylib.checkStart("cmd UUID");
         check_dylib.checkNext("uuid " ++ exp);
         test_step.dependOn(&check_dylib.step);
     }
     {
-        const dylib = simpleDylib(b, mode);
+        const dylib = simpleDylib(b, mode, target);
         dylib.strip = true;
         const check_dylib = dylib.checkObject(.macho);
         check_dylib.checkStart("cmd UUID");
@@ -30,10 +52,10 @@ fn testUuid(b: *Builder, test_step: *std.build.Step, mode: std.builtin.Mode, com
     }
 }
 
-fn simpleDylib(b: *Builder, mode: std.builtin.Mode) *LibExeObjectStep {
+fn simpleDylib(b: *Builder, mode: std.builtin.Mode, target: std.zig.CrossTarget) *LibExeObjectStep {
     const dylib = b.addSharedLibrary("test", null, b.version(1, 0, 0));
+    dylib.setTarget(target);
     dylib.setBuildMode(mode);
-    dylib.setTarget(.{ .cpu_arch = .aarch64, .os_tag = .macos });
     dylib.addCSourceFile("test.c", &.{});
     dylib.linkLibC();
     return dylib;